Revia overview

Revia works best when it is part of a broader recovery programme rather than a standalone solution. Many patients use it to support long-term behaviour change, especially after detoxification. Because outcomes depend on individual health status and treatment adherence, careful screening and ongoing monitoring are important.
This page explains what Revia is, how it works, how it is taken, and key safety information such as side effects and interactions. It also outlines how online pharmacy purchasing typically works in Denmark and what checks may be involved. The goal is to help you make an informed, safety-first decision.
What Revia is used for
Revia (naltrexone) is used to support treatment of alcohol dependence by reducing the rewarding effects of alcohol and helping curb cravings in some people. It may also be used in opioid dependence as part of relapse-prevention after a person is fully opioid-free. Use in opioid dependence requires particular caution because naltrexone can trigger sudden withdrawal if opioids are still present.
The medicine is generally prescribed for adults and is intended to be used with psychosocial support such as counselling, peer support, or structured therapy. It does not replace detoxification or emergency care for acute intoxication or withdrawal. Instead, it is one tool that can help maintain recovery and reduce relapse risk over time.
Not everyone responds the same way, and some people may not tolerate the medication. A clinician typically reviews your goals, medical history, and current medicines before recommending it. If you have ongoing opioid use or need opioid pain relief, an alternative approach may be safer.
Active ingredient and how it differs from similar medicines
The active ingredient in Revia is naltrexone hydrochloride. Naltrexone is an opioid receptor antagonist, meaning it blocks opioid receptors rather than activating them. This distinguishes it from opioid agonists (such as methadone) or partial agonists (such as buprenorphine) used in opioid use disorder treatment.
Because it blocks receptors, naltrexone can reduce the effects of opioids and may reduce the reinforcing effects of alcohol. It is not a controlled “replacement” opioid and is not intended to treat pain. If you require opioid analgesics, naltrexone can complicate pain management.
Some patients ask about “low-dose naltrexone” (LDN) for other conditions. Revia is a standard-dose product intended for approved addiction-related indications, and off-label use should be discussed with a qualified clinician. If you are considering any non-standard dosing, do not self-adjust without medical guidance.
History and origin
Naltrexone was developed following earlier work on opioid receptor pharmacology and the recognition that blocking opioid receptors could counteract opioid effects. Researchers explored antagonists as tools for both overdose reversal and longer-term relapse prevention. Over time, naltrexone became established for maintenance therapy in carefully selected patients.
The clinical rationale expanded when it was observed that opioid receptor signalling also plays a role in alcohol reward pathways. This led to the use of naltrexone in alcohol dependence for certain patients, particularly when cravings or reward-driven drinking patterns are prominent. Modern treatment approaches emphasise combining medication with behavioural support.
Revia is one of the brand presentations of naltrexone that has been used in clinical settings for many years. As with many established medicines, guidance has evolved to prioritise patient selection, liver safety considerations, and avoidance in situations where opioids are needed. In Denmark, clinicians typically follow national and EU-aligned prescribing standards.
Mechanism of action
Revia blocks primarily the mu-opioid receptor and also has activity at other opioid receptors. By occupying these receptors, it reduces the effects of externally taken opioids. In alcohol dependence, receptor blockade is thought to reduce some of the rewarding feedback that reinforces drinking.
The clinical effect is not the same as creating aversion; it does not make alcohol “poisonous.” Instead, many patients describe a reduced urge to continue drinking or less satisfaction from drinking. The degree of benefit varies, and some people notice little change.
Because receptor blockade can be overcome with high doses of opioids, attempting to “override” naltrexone is dangerous and can lead to overdose once the blockade wanes. This risk is one reason careful counselling is essential. Always tell healthcare providers you are taking naltrexone, especially before emergency care or surgery.
How to take Revia
Revia is taken by mouth as directed by a clinician, usually once daily, and can be taken with or without food. Some people find taking it with food helps reduce nausea. Consistency matters, so taking it at the same time each day can support adherence.
For opioid dependence, it is crucial that a person is opioid-free for an adequate period before starting, based on clinical assessment. Starting too soon can cause abrupt withdrawal symptoms. If there is any uncertainty about opioid exposure—including certain cough medicines or pain treatments—discuss this before the first dose.
If you miss a dose, typical advice is to take it when you remember unless it is close to the next scheduled dose, but individual instructions can differ. Do not double up without medical direction. If you stop and restart after a gap, speak to a clinician to confirm the safest way to resume.
Available forms and typical dosages
Revia is commonly supplied as oral tablets in a standard strength, though availability can vary by supplier and regulatory status. The prescriber selects a dose based on the indication, response, tolerability, and clinical guidelines. Dose adjustments may be considered if side effects occur.
Some patients use naltrexone intermittently or “targeted” around high-risk situations for alcohol use, but that approach should only be used if specifically recommended by a clinician. Self-directed changes can reduce effectiveness or increase risk. Your pharmacist can also help check instructions and suitability.
Because packaging and authorised presentations can vary, confirm the exact tablet strength and directions on your dispensed label. If the product appearance changes between refills, ask the pharmacy to verify that it is an equivalent authorised medicine. Never take tablets that appear damaged or that lack proper labelling.
How long it takes to work and how long effects last
Some people notice an effect on cravings within the first days, while for others it can take longer, especially as habits and triggers are addressed through counselling. The medication’s benefit is often most visible when combined with structured support. Response can be assessed over several weeks rather than a single day.
The receptor-blocking effect lasts beyond the time you “feel” anything, because naltrexone works by receptor occupancy rather than by producing a noticeable sensation. Even if you feel normal, opioid blockade may still be present. This matters for pain treatment and for overdose risk if opioids are taken.
If you are using Revia for alcohol dependence, the effect is generally intended to be continuous with daily dosing as advised. Do not assume that skipping doses is harmless. If you are considering stopping, discuss a plan that also supports relapse prevention.
How long Revia stays in the body
Naltrexone is metabolised in the liver into an active metabolite (often referenced as 6-beta-naltrexol) that can contribute to ongoing receptor blockade. Because of this, the functional effect can persist after the last dose. Clearance time can vary with liver function, dosing schedule, and individual metabolism.
As a practical safety point, you should tell clinicians you have taken naltrexone recently if you need pain control or emergency treatment. Opioid pain medicines may be less effective, and alternative strategies may be required. Planning ahead is particularly important for elective procedures.
If you have liver disease or abnormal liver tests, the medicine may remain in your system longer and the risk of adverse effects may increase. Your prescriber may recommend monitoring and may adjust treatment accordingly. Do not restart after a break without confirming safety if your health status has changed.
Scientific research and what it means for patients
Naltrexone has been studied in addiction treatment for decades, with research supporting its role as one option for relapse prevention in alcohol dependence and for selected patients with opioid dependence after detoxification. Studies generally show that benefits are modest to moderate and depend strongly on adherence and concurrent psychosocial care. It is therefore best viewed as part of a comprehensive plan rather than a guaranteed solution.
Research also highlights that different patients respond differently, influenced by patterns of use, co-existing mental health conditions, and social supports. Clinicians often reassess treatment after a trial period to see whether goals are being met. If benefit is limited, other evidence-based options may be more suitable.
Safety research has led to clear cautions regarding liver health and opioid use. Modern guidance emphasises screening, patient education, and follow-up to reduce preventable harms. A pharmacy’s role includes checking interactions and reinforcing safe use instructions.
Dependence, addiction potential, and misuse considerations
Revia does not produce euphoria and is not considered addictive in the way opioids, benzodiazepines, or stimulants can be. It does not cause physical dependence that leads to a typical withdrawal syndrome when stopped. However, stopping naltrexone may remove a layer of protection against relapse, so support planning remains important.
A key misuse risk is attempting to override receptor blockade with high doses of opioids. This can lead to life-threatening overdose, especially as naltrexone wears off or if a person’s opioid tolerance has decreased during abstinence. People who have been opioid-free are at heightened overdose risk if they return to prior doses.
If you have a history of overdose, polysubstance use, or unstable medical conditions, a clinician may recommend a different approach or closer monitoring. Always disclose substance use honestly to your prescriber and pharmacist. This helps tailor safer care rather than restricting it.
Side effects and what to watch for
Common side effects can include nausea, abdominal discomfort, headache, dizziness, fatigue, and sleep disturbances. Some people experience anxiety or irritability, particularly early in treatment. Many mild effects improve after the first one to two weeks, but persistent symptoms should be reviewed.
Because naltrexone is processed by the liver, liver-related side effects are a recognised concern. Seek medical advice promptly if you develop symptoms such as yellowing of the skin or eyes, dark urine, severe abdominal pain, or unusual persistent nausea. Your clinician may order liver function tests based on your history and risk factors.
Revia can also cause injection-site issues only for injectable formulations, which are different products from oral Revia tablets. For tablets, gastrointestinal effects are more typical. Any severe reaction, fainting, chest pain, or breathing difficulty should be treated as urgent and assessed immediately.
Who should not take Revia (contraindications and precautions)
Revia should not be taken by anyone currently using opioids, including illicit opioids or certain prescription opioid pain medicines, because it can precipitate withdrawal and block needed analgesia. It is also generally avoided in acute hepatitis or severe liver impairment. People with known hypersensitivity to naltrexone or tablet ingredients should not take it.
Extra caution is needed if you have liver disease, kidney problems, or a history of depression or suicidal thoughts. While naltrexone is not an antidepressant, mental health symptoms can influence adherence and relapse risk, and treatment plans should address both. Discuss all medical conditions and supplements with your clinician.
Pregnancy and breastfeeding require individualised assessment of risks and benefits. If you are pregnant, planning pregnancy, or breastfeeding, do not start or stop this medicine without medical advice. Safer alternatives or additional monitoring may be recommended depending on the situation.
Age and other restrictions
Revia is generally intended for adults, and use in minors is typically restricted and specialist-led. Age thresholds and practice standards can vary, but paediatric use is not routine. If the intended patient is under 18, a specialist evaluation is usually required.
Other restrictions include the need to avoid opioids and to plan for pain management. If you anticipate dental work, surgery, or injury that may require strong pain relief, inform the treating clinician well in advance. A medical alert card or note can be useful.
If you drive or operate machinery, be aware that dizziness or fatigue can occur, especially at the start of therapy. Assess how you respond before engaging in higher-risk activities. Avoid mixing with sedating substances unless a clinician confirms it is safe.
Allergic reactions and interactions (including alcohol)
Allergic reactions are uncommon but can occur with any medication. Signs may include rash, itching, swelling (especially of the face, lips, or throat), severe dizziness, or difficulty breathing. If these occur, seek urgent medical care and do not take another dose unless instructed.
Drug interactions are particularly important with any opioid-containing product, including some combination pain medicines and certain antidiarrhoeals. Always check labels and consult a pharmacist before taking new medicines, including over-the-counter products. Inform clinicians that you are taking naltrexone before receiving anaesthesia or emergency analgesia.
Revia is used in alcohol dependence and does not require complete abstinence to be pharmacologically “compatible” with alcohol, but drinking may still be harmful and can undermine recovery goals. Alcohol can worsen dizziness or sleep problems in some people. Discuss a realistic plan with your clinician, and seek help immediately if you feel at risk of relapse or harm.
Overdose risk and what to do
Taking more Revia than prescribed may increase side effects such as nausea, abdominal pain, dizziness, or confusion. If you suspect an overdose, contact emergency services or a poison information service promptly in Denmark, especially if severe symptoms occur. Keep the medication packaging available so responders can identify the product and strength.
The most serious risk scenario often involves opioids rather than naltrexone itself. Attempting to overcome naltrexone’s blocking effect with opioids is dangerous and can result in respiratory depression and death, particularly when the blockade diminishes. If opioids are taken and a person becomes very sleepy, slows breathing, or is difficult to wake, treat it as an emergency.
If you are supporting someone in treatment, it can help to discuss an emergency plan in advance. This includes recognising overdose signs and knowing local emergency numbers. Never delay emergency care while waiting to see if symptoms improve.
Storage, handling, and travel tips
Store Revia tablets in their original packaging, protected from moisture and excessive heat, and out of reach of children. Follow the storage instructions on the label, as they reflect the specific manufacturer’s stability guidance. Do not use tablets past the expiry date.
When travelling within Denmark or internationally, carry the medicine in its labelled packaging. This helps with identification and reduces issues at border checks or security screenings. Keep a copy of your prescription or dispensing record if available.
Dispose of unused or expired tablets through a pharmacy take-back option when possible. Avoid throwing medicines into household waste or flushing them, as this can contribute to environmental contamination. Your local Danish pharmacy can advise on proper disposal routes.
Buying Revia in Denmark: online availability, pricing, and ordering
In Denmark, medicines like naltrexone are often regulated, and whether Revia can be supplied without prescription depends on national rules, the product’s classification, and verification requirements. If a medicine is prescription-only, a legitimate online pharmacy will typically request a valid prescription or offer a structured clinical assessment where permitted. Any site offering guaranteed supply with no checks for a medicine that is normally prescription-controlled should be treated with caution.
People often compare the price of Revia across online pharmacies, but costs can vary due to brand versus generic availability, pack size, shipping, and included services (such as pharmacist support). As a general guide, prices seen across Danish-facing online sellers may range from moderate to higher for branded packs, while authorised generic naltrexone—when available—can be less expensive. Always prioritise regulated supply, clear labelling, and transparent contact details over unusually low pricing.
Buying through a reputable online pharmacy can offer privacy, convenient refills, and access to pharmacist guidance without needing to travel. It can also reduce missed doses by simplifying reordering. However, your safety depends on correct screening, accurate dispensing, and secure delivery.
To buy Revia through our online pharmacy, you typically choose your strength and quantity, complete a brief health questionnaire, and provide prescription details if required by Danish regulation. A pharmacist review is used to check for opioid use, liver concerns, and interactions before dispatch. After shipping, you can usually monitor delivery progress with package tracking so you know when to expect your order.
| Checkpoint | What a safe online purchase should include |
|---|---|
| Identity and legitimacy | Clear company details, pharmacist oversight, and regulated dispensing practices appropriate for Denmark |
| Clinical screening | Questions about opioid use, liver history, current medicines, and allergies before supply |
| Product quality | Proper labelling, batch/expiry information, and sealed packaging |
| Delivery transparency | Tracking availability and discreet, secure packaging |
Alternatives to Revia and when to consider them
Alternatives depend on the condition being treated and individual circumstances. For alcohol dependence, other medicines may be considered in some patients, and psychosocial interventions remain foundational. For opioid dependence, opioid agonist therapies are often used and may be more appropriate for many individuals, especially when ongoing opioid exposure risk is high.
Non-pharmacological options include structured counselling, cognitive behavioural strategies, contingency management, mutual-help groups, and addressing co-existing mental health conditions. Often the best plan combines several approaches. If Revia is not tolerated or not effective after an adequate trial, revisiting the overall treatment plan is sensible.
Do not switch treatments abruptly without clinical guidance, particularly if opioids are involved. A clinician can help you compare benefits, risks, and practicalities such as follow-up frequency and monitoring. Your pharmacist can support medication comparisons and interaction checks, but diagnosis and treatment selection should be clinician-led.
Frequently Asked Questions
What is Revia, and what condition is it typically prescribed for?
Revia is a brand name for naltrexone, a medicine used as part of a broader treatment plan for alcohol dependence in some patients. It is usually prescribed alongside counselling or structured support rather than as a stand-alone solution. Your prescriber will confirm whether it fits your goals, health history, and other medicines.
Do I need to be opioid-free before starting Revia?
Yes—people must be free of opioids before starting naltrexone, because it can trigger sudden opioid withdrawal and block opioid pain medicines from working. Tell your clinician about any opioid use (including some cough or diarrhoea medicines) and any recent opioid treatment. If there is uncertainty, a clinician may use testing or a supervised plan to reduce risk.
Can I take Revia if I might need opioid pain relief for surgery or an injury?
Revia can make opioid pain medicines less effective, which can complicate emergency or planned pain management. If you have upcoming surgery or a higher likelihood of needing opioid analgesia, discuss this in advance with your prescriber. Do not stop or restart Revia on your own—your care team can advise on timing and safer alternatives.
What should I do if I miss a dose of Revia?
If you miss a dose, take it when you remember unless it is close to your next scheduled dose. Do not take a double dose to make up for a missed tablet. If missed doses happen often, ask your pharmacist or prescriber for strategies to help you stay on track.
What are common side effects people notice with Revia?
Some people experience nausea, headache, dizziness, tiredness, or sleep changes, especially when first starting treatment. Many side effects are mild and improve over time, but persistent or worsening symptoms should be discussed with a clinician. Seek urgent help for signs of a serious reaction, such as trouble breathing, swelling, or severe rash.
Is Revia safe for people with liver problems?
Naltrexone is processed by the liver, so existing liver disease can affect whether it is appropriate and how it is monitored. Your prescriber may order baseline and follow-up liver tests, particularly if there is a history of hepatitis or heavy alcohol use. Contact a clinician promptly if you develop symptoms that could suggest liver issues, such as yellowing of the skin or eyes or dark urine.
Can I drink alcohol while taking Revia?
Revia is not a substitute for support to reduce drinking, and it does not prevent alcohol intoxication. Some people may still drink while taking it, but your treatment plan should be agreed with your prescriber and aligned with your goals. If you are trying to cut down, pairing medication with behavioural support usually improves outcomes.
Can I buy Revia online in Denmark?
In Denmark, medicines like Revia are often supplied under rules that may require a valid prescription and pharmacy verification. If you choose to order online, use a regulated pharmacy service that checks eligibility, provides counselling access, and handles medicines according to local requirements. Avoid websites offering Revia “without prescription,” as this can be unsafe and may not comply with Danish regulations.
Pharmacist Review
The information on this Revia product page has been reviewed for pharmaceutical accuracy and patient safety by Mette Louise Andersen, Cand.pharm. (Master of Pharmacy), Licensed Pharmacist (Registry No. DK-AP-784213), in line with commonly accepted practice and regulatory expectations in Denmark, including guidance associated with the Danish Medicines Agency (Lægemiddelstyrelsen).
Review date: 17/07/2026
What was checked
- Consistency of key information on intended use, dosing instructions, and practical administration details for Revia.
- Prominent safety points, including contraindications, precautions, and clinically relevant interactions.
- Clarity of patient-facing guidance on side effects, missed doses, and when to seek urgent medical help.
- Appropriateness of general statements about how the medicine works, avoiding overstatement and ensuring balanced expectations.
Important safety note
This material is provided for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a doctor or other qualified healthcare professional to confirm that Revia is appropriate for you, especially if you use other medicines, have underlying health conditions, are pregnant or breastfeeding, or experience unexpected symptoms.
Pharmacy Location and Opening Hours
Store address for Revia: Østergade 18, 1050 København K, Hovedstaden, DK
Visit our pharmacy during the hours below (local time).
| Day | Hours |
|---|---|
| Monday–Friday | 09:00–18:00 |
| Saturday | 10:00–15:00 |